Lane keeping assist system(LKAS) of electric bus must be equipped in Taiwan’s E-Bus DMIT pilot project. LKAS can detect lane boundary and intervene steering system actively for the purpose of correcting the bus back into its lane when a lane departure is about to occur. Mechanical and Mechatronics Systems Research Lab, ITRI developed Lane Keeping Assist System. ADAS controller was embedded with self-developed lane keeping control algorithm.Domestic electric power steering (EPS) motor integrated with original steering mechanism was adopted as steering by-wire solution. This system operates regularly and steadily at the speed range from 40 ~ 90 km/h and can be mandatory terminated by applying torque on steering wheel, which ensures drivers always own the highest priority to handle vehicle. LKAS has transferred to domestic electric bus manufacturers already.